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*** LAB NEWS ***
NEW MOLECULAR TEST
OFFERED FOR THROMBOTIC TENDENCY
The Molecular Genetics Laboratory at University Hospital at Stony
Brook is pleased to announce the availability of a test for the
prothrombin gene 20210A mutation. This mutation is located in the
3'
untranslated region of the gene and is an important risk factor
for
venous thrombosis in general in the Caucasian population. In a recent
study by Kapur et al. (1), 19% of subjects with a history of venous
thrombosis had the 20210 G to A mutation compared to 2% of control
subjects.
Specimen requirements: One lavender top tube. No refrigeration
is
necessary. A consent form signed by the patient must be included
to
comply with New York State regulations.
The cost of the test is $125 and the turnaround time is 14 days.
The
test can be ordered individually ($125) or together with Factor
V
Leiden ($225 for both assays when performed on the same specimen).
Please contact our laboratory at 631-444-3747 or FAX 631-444-3419
for
more information.
1. Kapur RK, Mills LA, Spitzer SG, Hultin MB. A prothrombin
gene
mutation is significantly associated with venous thrombosis.
Arterioscler Thromb Vasc Biol. 1997; 17:2875-2879.
Silvia G. Spitzer, Ph. D.
Head, Molecular Diagnostics Laboratory
Dept. of Pathology
SUNY at Stony Brook
Stony Brook, NY 11794-8691
FAX: 631-444-3419
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